Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14586198 | 0.89 | PRMT6 (0.42) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL12362134 | 0.87 | PRMT6 (0.43) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13407308 | 0.85 | NPC1 (0.41) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13859068 | 0.83 | NPC1 (0.42) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13407338 | 0.79 | ICAM1 (0.32) | HSD17B10 | |
| SCHEMBL20814635 | 0.79 | DPP4 (0.44) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2027946 | 0.79 | DPP4 (0.44) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL18785539 | 0.77 | NPC1 (0.38) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13621245 | 0.77 | DPP4 (0.41) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL20461843 | 0.75 | PRMT6 (0.48) | NPC1RAB9ASMN1; SMN2TP53PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700643-B2 | Polymerisable thieno[3,2-b]thiophenes | MERCK PATENT GMBH (DE) | 2010-04-20 | — | — | US | disclosed |