Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407338 | 0.93 | ICAM1 (0.32) | MAPK1HSD17B10ICAM1SELEVCAM1 | |
| SCHEMBL16004512 | 0.92 | MAPK1 (0.37) | MAPK1HSD17B10ICAM1SELEVCAM1 | |
| SCHEMBL13407340 | 0.89 | ESR1 (0.35) | MAPK1HSD17B10ICAM1SELEVCAM1 | |
| SCHEMBL13407341 | 0.84 | ESR1 (0.39) | — | |
| SCHEMBL14479816 | 0.82 | ALDH1A1 (0.37) | HSD17B10 | |
| SCHEMBL13407303 | 0.82 | ALDH1A1 (0.37) | HSD17B10 | |
| SCHEMBL9980122 | 0.80 | MAPK1 (0.42) | MAPK1HSD17B10ICAM1SELEVCAM1 | |
| SCHEMBL26816216 | 0.75 | HSD17B10 (0.33) | MAPK1HSD17B10 | |
| SCHEMBL13407304 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL14854116 | 0.74 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700643-B2 | Polymerisable thieno[3,2-b]thiophenes | MERCK PATENT GMBH (DE) | 2010-04-20 | — | — | US | disclosed |