Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407428 | 0.86 | KCNH2 (0.43) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4559736 | 0.86 | KCNH2 (0.42) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4559739 | 0.86 | KCNH2 (0.42) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4559738 | 0.86 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL14498845 | 0.85 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL14498890 | 0.84 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL13407434 | 0.84 | KCNH2 (0.52) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4557621 | 0.83 | KCNH2 (0.52) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4557622 | 0.83 | KCNH2 (0.52) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4557620 | 0.83 | KCNH2 (0.52) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081650-A1 | Antimicrobial Compounds | ELANE, NISCH, PIGS | KCNH2 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.