PIGS

GPI-anchor transamidase component PIGS · Q96S52 · PIGS on Sugi Atlas →

0 patent compounds predicted against PIGS, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PIGS by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage (PLACE030) PHASE3ACTIVE_NOT_RECRUITING
Vaccine Treatment for Surgically Resected Pancreatic Cancer PHASE1/PHASE2COMPLETED
Open-label Investigation of the Safety and Effectiveness of DIABECELL® in Patients With Type 1 Diabetes Mellitus PHASE1/PHASE2COMPLETED
Vaccine Treatment for Advanced Malignant Melanoma PHASE1/PHASE2COMPLETED
CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk PHASE1/PHASE2RECRUITING
Vaccine Treatment for Hormone Refractory Prostate Cancer PHASE1/PHASE2COMPLETED
CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular Carcinoma PHASE1/PHASE2NOT_YET_RECRUITING
Depletion of Serum Amyloid P Component to Enhance the Immune Response to DNA Vaccination PHASE1/PHASE2COMPLETED
Safety and Effect of Oral RVX000222 in Subjects With Fabry Disease PHASE1/PHASE2WITHDRAWN
Anticoagulation With rNAPc2 to Eliminate MACE/TIMI 32 PHASE2COMPLETED
Bioequivalence Study of a Generic Enoxaparin Sodium to Clexane® After Single Subcutaneous Dose in Healthy Human Subjects PHASE1COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Remote Ischaemic Conditioning in Endovascular Recanalization for Proximal Anterior Circulation Occlusion Study PHASE1UNKNOWN
CINRYZE as a Donor Pre-treatment Strategy in Kidney Recipients of KDPI>60% PHASE1UNKNOWN
Influenza Antiviral DAS181-F03 PHASE1COMPLETED
Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy PHASE1COMPLETED
Ex Vivo Perfusion of Gene-Edited Porcine Livers in Patients With Severe Hepatic Failure EARLY_PHASE1ACTIVE_NOT_RECRUITING
Factor IX as Adjunctive Therapy to Emicizumab (EMIX) EARLY_PHASE1COMPLETED
The Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH) nanCOMPLETED
A Real-world, Multi-center, Prospective, Observational Study for PNH in China nanCOMPLETED
Transfer of GPI-Linked Proteins to Transfused Patients With Paroxysmal Nocturnal Hemoglobinuria nanCOMPLETED
The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty nanUNKNOWN
Human Sperm Binding to Transgenic Mouse Eggs nanCOMPLETED
Effects of the Bone Tissue on the Haemostasis nanUNKNOWN
Matrix Metalloproteinases in Patients With Critical Limb Ischemia Undergoing Surgical Revascularization nanCOMPLETED
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease nanUNKNOWN
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Preparation of IPSC for Cell Gene Editing for the Treatment of AATD nanENROLLING_BY_INVITATION
Screening of Lysosomal Storage Disorders Diseases in Minority Groups nanUNKNOWN
Perioperative Plasma Levels of Glycocalyx Markers in Colon Surgery. nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PIGS binder may also engage these)

ProteinNameSimilarity
Q5XI31 1.000 Q5XI31 →
Q3SZL5 1.000 Q3SZL5 →
Q6PD26 1.000 Q6PD26 →
Q6AXS4 0.984 Q6AXS4 →
Q9WTZ2 0.983 Q9WTZ2 →
Q6NRB9 0.983 Q6NRB9 →
Q6UPR8 0.983 Q6UPR8 →
Q3V1T4 0.982 Q3V1T4 →
Q0DJC5 0.982 Q0DJC5 →
Q5R7K6 0.982 Q5R7K6 →
Q9R1Q9 0.982 Q9R1Q9 →
P81134 0.981 P81134 →
O95477 0.981 O95477 →
ERMP1 Endoplasmic reticulum metallopeptidase 1 0.981 landscape →
EMC1 ER membrane protein complex subunit 1 0.981 landscape →
Q9Z2A8 0.981 Q9Z2A8 →
Q9WTZ3 0.981 Q9WTZ3 →
Q9CRG1 0.980 Q9CRG1 →
P2RX5 P2X purinoceptor 5 0.980 landscape →
Q765H6 0.980 Q765H6 →
Q32P28 0.980 Q32P28 →
Q5SNQ7 0.980 Q5SNQ7 →
Q61586 0.980 Q61586 →
Q8K1S3 0.980 Q8K1S3 →
Q9BRR3 0.980 Q9BRR3 →
Q640M6 0.980 Q640M6 →
Q4KLM6 0.980 Q4KLM6 →
Q3UVK0 0.979 Q3UVK0 →
Q60432 0.979 Q60432 →
Q66K08 0.979 Q66K08 →