Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | HPGD | P15428 | 6/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL503706 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28006176 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL3399561 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL217212 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL10490726 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL1932763 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL5142971 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL12477386 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9183232 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8777 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108441-A1 | PRESERVATIVE SYSTEM | L'OREAL (FR) | 2026-04-23 | — | — | US | claimed |
| US-20250388765-A1 | Water Washable Ink or Paint | CRAYOLA LLC (US) | 2025-12-25 | — | — | US | claimed |
| WO-2025229086-A1 | ADHESIVE COSMETIC COMPOUNDS AND USES THEREOF | SKINOSIVE (FR) | 2025-11-06 | — | — | WO | claimed |
| EP-4633395-A1 | MOUTHPIECE FOR AN AEROSOL-GENERATING SYSTEM | Philip Morris Products S.A. (CH) | 2025-10-22 | — | — | EP | claimed |
| US-12318463-B2 | Compositions and methods for treating canker sores | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-06-03 | — | — | US | claimed |
| CN-120060771-A | High-resistant Wen Qingzhi stealth coating material and preparation method thereof | 山东中航泰达复合材料有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120054539-A | Residual oil hydrodesulfurization catalyst, preparation method and application | 中国石油化工股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| EP-3801455-B1 | MILD COMPOSITION FOR USE IN TOPICAL TREATMENT OF SKIN AND NAIL DISORDERS CAUSED BY VIRUS AND FUNGUS | EVIDERM INST AB (SE) | 2025-05-21 | — | — | EP | claimed |
| CN-117224412-B | Oil-control and anti-dandruff composition and application thereof | 广州美尔生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| EP-3810067-B1 | METHODS OF INHIBITING MICROBIAL INFECTIONS USING ZINC-CONTAINING COMPOSITIONS | TRIUMPH PHARMACEUTICALS INC (US) | 2025-04-16 | — | — | EP | claimed |
| US-4355823-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1982-10-26 | — | — | US | claimed |
| EP-0059335-A1 | Novel process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)-propionic ester | Tanabe Seiyaku Co., Ltd. (JP) | 1982-09-08 | — | — | EP | claimed |
| US-4203619-A | HEATING THE COATING CONTAINING A CHROMOGENIC MATERIAL, COOLING AND SETTING; SOLVENT-FREE | THE MEAD CORPORATION (US) | 1980-05-20 | — | — | US | claimed |
| US-4075015-A | Light sensitive mass and process for its production | SWISS ALUMINIUM LTD. (CH) | 1978-02-21 | — | — | US | claimed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| US-4022624-A | N-(AMINOALKYL)-LACTAM | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-10 | — | — | US | claimed |
| US-RE29157-E | High temperature resistant polychloroprene adhesive resin | SCHENECTADY CHEMICALS, INC. (US) | 1977-03-22 | — | — | US | claimed |
| US-3996142-A | Smoke and fire retardants for halogen-containing plastic compositions comprising the reaction product of magnesium oxide and a zinc salt of an acid | NL INDUSTRIES, INC. (US) | 1976-12-07 | — | — | US | claimed |
| US-3949072-A | PHENOLATE, SALICYLATE, RESORCINOL, ZINC COMPOUND | TENTA LOUIS T | 1976-04-06 | — | — | US | claimed |
| US-3939488-A | Method of manufacturing semiconductor device and resulting product | HITACHI, LTD. (JA) | 1976-02-17 | — | — | US | claimed |