Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.91 |
| ▸ | HPGD | P15428 | 5/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL11315590 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL1932763 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL5142971 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9183232 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL299753 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL217212 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL10490726 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL12477386 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL106935 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253681-B1 | INTERFACIAL LAYER AND COATING SOLUTION FOR FORMING THE SAME | XEROX CORP (US) | 2015-07-08 | — | — | EP | claimed |
| US-8273514-B2 | Interfacial layer and coating solution for forming the same | XEROX CORPORATION (US) | 2012-09-25 | — | — | US | claimed |
| US-20100297543-A1 | INTERFACIAL LAYER AND COATING SOLUTION FOR FORMING THE SAME | XEROX CORPORATION (US) | 2010-11-25 | — | — | US | claimed |
| EP-2253681-A1 | Interfacial layer and coating solution for forming the same | Xerox Corporation (US) | 2010-11-24 | — | — | EP | claimed |
| US-7382520-B2 | Charge control agents in display media | XEROX CORPORATION (US) | 2008-06-03 | — | — | US | claimed |
| US-20070047063-A1 | Charge control agents in display media | XEROX CORPORATION (US) | 2007-03-01 | — | — | US | claimed |
| JP-2286716-A | — | — | None | — | — | JP | disclosed |
| US-10613450-B2 | Crash cooling method to prepare toner | LEXMARK INTERNATIONAL, INC. (US) | 2020-04-07 | — | — | US | disclosed |
| US-10606182-B2 | Crash cooling method to prepare toner | LEXMARK INTERNATIONAL, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-10591834-B2 | Crash cooling method to prepare toner | LEXMARK INTERNATIONAL, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-10591833-B2 | Crash cooling method to prepare toner | LEXMARK INTERNATIONAL, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-10591831-B2 | Crash cooling method to prepare toner | LEXMARK INTERNATIONAL, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-10591832-B2 | Crash cooling method to prepare toner | LEXMARK INTERNATIONAL, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| EP-1615082-A2 | Dry electrophotographic toners comprising amphipathic copolymers having acidic functionality | Samsung Electronics Co., Ltd. (KR) | 2006-01-11 | — | — | EP | disclosed |
| US-20060003247-A1 | Dry electrophotographic toners comprising amphipathic copolymers having acidic functionality | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-01-05 | — | — | US | disclosed |
| US-20060003246-A1 | Dry electrophotographic toners comprising amphipathic copolymers having basic functionality | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-01-05 | — | — | US | disclosed |
| US-20050250029-A1 | Negatively charged coated electrographic toner particles and process | S-PRINTING SOLUTION CO., LTD. (KR) | 2005-11-10 | — | — | US | disclosed |
| EP-1594011-A2 | Negatively charged coated electrographic toner particles | Samsung Electronics Co., Ltd. (KR) | 2005-11-09 | — | — | EP | disclosed |
| JP-H02286716-A | PREPARATION OF POLYKETONE COMPOUND | BRITISH PETROLEUM CO PLC:THE | 1990-11-26 | — | — | JP | disclosed |
| US-4306875-A | Salts of basic dyes, preparation and uses of same | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |