Sugi Predict

Sugi Predict / Compounds / SCHEMBL134085

SCHEMBL134085

SCHEMBL134085

CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2cc3c(cc21)-c1ccccc1C3(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ ESR1 P03372 1/20 0.35
▸ ESR2 Q92731 1/20 0.35
▸ CNR1 P21554 4/20 0.33
▸ PDK2 Q15119 3/20 0.33
▸ MMP2 P08253 5/20 0.33
▸ MMP9 P14780 5/20 0.33
▸ MMP8 P22894 2/20 0.33
▸ MMP13 P45452 2/20 0.33
▸ APEX1 P27695 1/20 0.32
▸ CNR2 P34972 3/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14984343 0.88 ESR1 (0.34) MEN1KMT2ALMNAKDM4EMAPT
SCHEMBL3811348 0.88 PDK2 (0.37) MEN1KMT2ALMNAKDM4EMAPT
SCHEMBL10049649 0.87 MEN1 (0.39) MEN1KMT2ALMNAKDM4EMAPT
SCHEMBL13892733 0.86 MEN1 (0.39) MEN1KMT2ALMNACNR1PDK2
SCHEMBL24257913 0.86 PDK2 (0.41) MEN1KMT2ACNR1PDK2MMP2
SCHEMBL18821380 0.84 APEX1 (0.42) MEN1KMT2ACNR1PDK2MMP2
SCHEMBL14060137 0.84 APEX1 (0.42) MEN1KMT2ACNR1PDK2MMP2
SCHEMBL23759843 0.83 PDK2 (0.43) MEN1KMT2ASMN1; SMN2PDK2MMP2
SCHEMBL1795297 0.83 PDK2 (0.43) MEN1KMT2ASMN1; SMN2PDK2MMP2
SCHEMBL31531021 0.83 PDK2 (0.43) MEN1KMT2ASMN1; SMN2PDK2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2838929-B1 POLYMERS CONTAINING SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS MERCK PATENT GMBH (DE) 2023-06-14 — — EP disclosed
US-20220119590-A1 POLYMERS WITH AMINE-GROUP-CONTAINING REPEATING UNITS MERCK PATENT GMBH (DE) 2022-04-21 — — US disclosed
US-20210277176-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER MERCK PATENT GMBH (DE) 2021-09-09 — — US disclosed
EP-2603540-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 — — EP disclosed
EP-2838930-B1 POLYMERS CONTAINING SUBSTITUTED OLIGO-TRIARYLAMINE UNITS AND ELECTROLUMINESCENCE DEVICES CONTAINING SUCH POLYMERS MERCK PATENT GMBH (DE) 2020-10-14 — — EP disclosed
WO-2020011701-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER MERCK PATENT GMBH (DE) 2020-01-16 — — WO disclosed
US-20190296242-A1 POLYMERS WITH ASYMMETRIC REPEATING UNITS MERCK PATENT GMBH (DE) 2019-09-26 — — US disclosed
WO-2018099847-A1 POLYMERS WITH ASYMMETRIC REPEATING UNITS MERCK PATENT GMBH (DE) 2018-06-07 — — WO disclosed
US-9815940-B2 Polymers containing substituted triarylamine units and electroluminescent devices containing said polymers MERCK PATENT GMBH (DE) 2017-11-14 — — US disclosed
US-9815940-B2 Polymers containing substituted triarylamine units and electroluminescent devices containing said polymers MERCK PATENT GMBH (DE) 2017-11-14 — — US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 — — US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 — — US disclosed
WO-2013156130-A1 POLYMERS CONTAINING SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS MERCK PATENT GMBH (DE) 2013-10-24 — — WO disclosed
US-20130228767-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK 2013-09-05 — — US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 — — US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 — — US disclosed
US-20120061617-A1 POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF MERCK PATENT GMBH (DE) 2012-03-15 — — US disclosed
US-20120061617-A1 POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF MERCK PATENT GMBH (DE) 2012-03-15 — — US disclosed
US-20120056170-A1 COMPOSITION COMPRISING AT LEAST ONE EMITTER COMPOUND AND AT LEAST ONE POLYMER HAVING CONJUGATION-INTERRUPTING UNITS MERCK PATENT GMBH (DE) 2012-03-08 — — US disclosed
WO-2010136110-A2 POLYMERS COMPRISING SUBSTITUTED INDENOFLUORENE DERIVATES AS STRUCTURAL UNITS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF MERCK PATENT GMBH (DE) 2010-12-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120061617-A1 POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF PPID, PCID2, OCIAD1 MEN1 4773/4885KMT2A 4490/4885LMNA 1722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.