Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23254671 | 0.88 | CYP2C19 (0.33) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL134085 | 0.87 | MEN1 (0.40) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL23254341 | 0.85 | — | — | |
| SCHEMBL13041967 | 0.82 | LPL (0.44) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL20233471 | 0.81 | PDK2 (0.36) | SMN1; SMN2PDK2MMP2MMP9 | |
| SCHEMBL12443262 | 0.81 | CNR1 (0.33) | CNR1CNR2 | |
| SCHEMBL14735970 | 0.79 | PDK2 (0.40) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6060722 | 0.79 | PDK2 (0.40) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6060767 | 0.79 | PDK2 (0.40) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6060780 | 0.79 | PDK2 (0.40) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603540-B1 | POLYMERS WITH CARBAZOLE STRUCTURAL UNITS | MERCK PATENT GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |
| WO-2012019724-A1 | POLYMERS WITH CARBAZOLE STRUCTURAL UNITS | MERCK PATENT GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |