Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13408637 | 0.88 | GAA (0.67) | ALDH1A1GPBAR1GAATSHRMEN1 | |
| SCHEMBL13287103 | 0.87 | GAA (0.68) | ALDH1A1HPGDGAATSHRMEN1 | |
| SCHEMBL13391211 | 0.84 | ALDH1A1 (0.69) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL13621122 | 0.84 | CYP2C19 (0.72) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL20160112 | 0.84 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL15692586 | 0.82 | CYP2D6 (0.56) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL3392745 | 0.81 | ALDH1A1 (0.74) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL13138659 | 0.81 | ALDH1A1 (0.74) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL10212124 | 0.80 | NPC1 (0.68) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 | |
| SCHEMBL22616973 | 0.79 | ALDH1A1 (0.69) | ALDH1A1RAB9ANPC1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | CELTAXSYS, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | PMAIP1, CDC42, DCX | ALDH1A1 3761/4885RAB9A 826/4885NPC1 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.