Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727493 | 0.83 | GAK (0.61) | IDO1GAKCCNCCDK8 | |
| SCHEMBL2621791 | 0.81 | GAK (0.46) | GAKIRAK4CCNCCDK8AAK1 | |
| SCHEMBL25826719 | 0.78 | DOT1L (0.48) | IRAK4 | |
| SCHEMBL25460788 | 0.78 | GAK (0.46) | IDO1GAKCCNCCDK8AAK1 | |
| SCHEMBL12282776 | 0.76 | MAPT (0.47) | IRAK4AAK1 | |
| SCHEMBL21462116 | 0.75 | GAK (0.47) | IDO1GAKCCNCCDK8 | |
| SCHEMBL25835191 | 0.75 | IRAK4 (0.40) | IDO1IRAK4 | |
| SCHEMBL21138127 | 0.75 | CCNC (0.45) | IDO1GAKCCNCCDK8AAK1 | |
| SCHEMBL31241566 | 0.74 | IDO1 (0.44) | IDO1GAKCCNCCDK8 | |
| SCHEMBL25826717 | 0.74 | IP6K1 (0.48) | IRAK4CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |