SCHEMBL25826719

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24010781	0.84	DOT1L (0.63)	DOT1LIP6K1EGFRALDH1A1HSD17B10
	SCHEMBL24003975	0.81	DOT1L (0.50)	DOT1LIP6K1EGFRMEN1ALDH1A1
	SCHEMBL2621791	0.78	GAK (0.46)	IRAK4EGFRLMNAACVR1
	SCHEMBL13409355	0.78	IDO1 (0.50)	IRAK4
	SCHEMBL25826712	0.78	PDE3B (0.44)	DOT1LIP6K1EGFRALDH1A1MAPK1
	SCHEMBL12282776	0.74	MAPT (0.47)	IRAK4MEN1KMT2AACVR1
	SCHEMBL12240676	0.74	IP6K1 (0.50)	DOT1LIP6K1EGFRMEN1ALDH1A1
	SCHEMBL25820108	0.73	IP6K1 (0.43)	DOT1LIP6K1EGFRMEN1ALDH1A1
	SCHEMBL25835191	0.72	IRAK4 (0.40)	IRAK4
	SCHEMBL1862289	0.72	DOT1L (0.50)	DOT1LIP6K1EGFRMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.