Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409382 | 0.92 | ATM (0.38) | ATMTDP1MAPTTSHRL3MBTL1 | |
| SCHEMBL13409727 | 0.78 | ATM (0.36) | ATMMAPTTSHRL3MBTL1BTK | |
| SCHEMBL13409365 | 0.77 | BCHE (0.43) | ATMMAPTTSHRL3MBTL1ACHE | |
| SCHEMBL12779577 | 0.75 | CYP1A2 (0.44) | ATMTDP1MAPTBTKKDM4E | |
| SCHEMBL13728674 | 0.73 | ATM (0.47) | ATMTDP1MAPTTSHRACHE | |
| SCHEMBL8274241 | 0.71 | KMT2A (0.39) | ATMTDP1MAPTTSHRL3MBTL1 | |
| SCHEMBL8272970 | 0.69 | ATM (0.37) | ATMTDP1MAPTTSHRKDM4E | |
| SCHEMBL15647796 | 0.67 | ATM (0.40) | ATMTDP1TSHRL3MBTL1ACHE | |
| SCHEMBL13966259 | 0.65 | ATM (0.56) | ATMTDP1MAPTTSHRL3MBTL1 | |
| SCHEMBL9169032 | 0.65 | ACHE (0.60) | TDP1TSHRACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |