Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276513 | 0.77 | — | — | |
| SCHEMBL11765799 | 0.70 | SMN1; SMN2 (0.34) | SMN1; SMN2KMT2ACA14 | |
| SCHEMBL11592041 | 0.67 | TSHR (0.39) | SMN1; SMN2KMT2ACA14 | |
| SCHEMBL7792286 | 0.66 | — | — | |
| SCHEMBL20931243 | 0.66 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ACA14 | |
| SCHEMBL27515461 | 0.64 | — | — | |
| SCHEMBL31324750 | 0.64 | — | — | |
| SCHEMBL27592716 | 0.64 | — | — | |
| SCHEMBL222114 | 0.64 | — | — | |
| SCHEMBL29774743 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691907-B2 | Methods and composition based on discovery of metabolism of nitroglycerin | DUKE UNIVERSITY (US) | 2010-04-06 | — | — | US | disclosed |