Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13392378 | 0.93 | MLNR (0.65) | MLNRGHSR | |
| SCHEMBL73789 | 0.93 | MLNR (0.59) | MLNRGHSR | |
| SCHEMBL12220298 | 0.92 | MLNR (0.64) | MLNRGHSR | |
| SCHEMBL91166 | 0.87 | MLNR (0.58) | MLNRGHSR | |
| SCHEMBL12220293 | 0.87 | MLNR (0.72) | MLNR | |
| SCHEMBL91248 | 0.85 | MLNR (0.71) | MLNRGHSR | |
| SCHEMBL21417689 | 0.84 | MLNR (0.62) | MLNRGHSR | |
| SCHEMBL73302 | 0.84 | MLNR (0.62) | MLNRGHSR | |
| SCHEMBL73799 | 0.84 | MLNR (0.64) | MLNRGHSR | |
| SCHEMBL91253 | 0.84 | MLNR (0.57) | MLNRGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093720-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR TREATMENT OF GASTROINTESTINAL DYSMOTILITY DISORDERS | MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED (IE) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093720-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR TREATMENT OF GASTROINTESTINAL DYSMOTILITY DISORDERS | MLNR, GIPR, GPR39 | MLNR 1/4885GHSR 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.