SCHEMBL1341202

SCHEMBL1341202

C=CCC1=CC=CCC1=S

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5088328 0.83
SCHEMBL6764541 0.82
SCHEMBL9419618 0.78
SCHEMBL55040 0.77
SCHEMBL1797594 0.76 KDM4E (0.31)
SCHEMBL8703474 0.76
SCHEMBL9405105 0.74
SCHEMBL1706668 0.73
SCHEMBL6689441 0.73
SCHEMBL6266389 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666975-B1 Method of manufacturing toner RICOH CO LTD (JP) 2018-11-07 EP disclosed
EP-1903403-B1 Image forming apparatus and process cartridge RICOH CO LTD (JP) 2015-11-04 EP disclosed
EP-1640809-B1 Toner manufacturing method, image forming method, image forming apparatus, and process cartridge RICOH CO LTD (JP) 2015-08-05 EP disclosed
US-8492063-B2 Method of manufacturing toner RICOH COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-8309290-B2 agglomeration and fusion of least two kinds of resin particulates and particles of the coloring agent dispersed in an aqueous medium, a first resin particulate among the two kinds of resin particulates including a second resin particulate containing a resin having a polyester skeleton and the wax RICOH COMPANY, LTD. (JP) 2012-11-13 US disclosed
US-8192911-B2 Method of manufacturing toner and toner RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-8187785-B2 Method of manufacturing toner RICOH COMPANY, LTD. (JP) 2012-05-29 US disclosed
US-8062821-B2 Toner, and process cartridge and image forming apparatus using the same RICOH COMPANY, LIMITED (JP) 2011-11-22 US disclosed
EP-1835351-B1 Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method RICOH CO LTD (JP) 2011-09-07 EP disclosed
US-7817955-B2 Image forming apparatus for securing good cleaning performance without cleaning blade abrasion RICOH COMPANY LIMITED (JP) 2010-10-19 US disclosed
EP-0778284-A2 New 7-beta-substituted-4-aza-5alpha-androstan-3-ones as 5alpha-reductase inhibitors MERCK & CO. INC. (US) 1997-06-11 EP disclosed
EP-0576603-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO. INC. (US) 1994-01-05 EP disclosed
EP-0572166-A1 New 7beta-substituted-4-aza-5a-androstan-3-ones as 5a-reductase inhibitors MERCK & CO. INC. (US) 1993-12-01 EP disclosed
WO-1993023039-A1 SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS MERCK & CO., INC. (US) 1993-11-25 WO disclosed
WO-1993023420-A1 NEW 7β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS MERCK & CO., INC. (US) 1993-11-25 WO disclosed
WO-1992018132-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR MERCK & CO., INC. (US) 1992-10-29 WO disclosed
WO-1992016213-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO., INC. (US) 1992-10-01 WO disclosed
WO-1992016233-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO., INC. (US) 1992-10-01 WO disclosed
US-5151430-A Specific 17β-thiobenzoyl-4-aza-5α-androst-1-en-3-ones as antiandrogen agents MERCK & CO., INC. (US) 1992-09-29 US disclosed
EP-0462664-A2 Specific 17beta-thiobenzoyl-4-aza-5alpha-androst-1-en-3-ones as antiandrogenic agents MERCK & CO. INC. (US) 1991-12-27 EP disclosed