⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797594 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL1341202 | 0.78 | CYP3A4 (0.30) | — | |
| SCHEMBL14390433 | 0.74 | — | — | |
| SCHEMBL11134061 | 0.73 | — | — | |
| SCHEMBL8599928 | 0.73 | — | — | |
| SCHEMBL8626634 | 0.72 | — | — | |
| SCHEMBL2143543 | 0.71 | — | — | |
| SCHEMBL27987753 | 0.70 | — | — | |
| SCHEMBL31450759 | 0.70 | — | — | |
| SCHEMBL27499909 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376724-A | Aromatic resin additive; impact strength | GENERAL ELECTRIC COMPANY (US) | 1994-12-27 | — | — | US | claimed |
| US-5376724-A | Aromatic resin additive; impact strength | GENERAL ELECTRIC COMPANY (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0417510-A1 | Polyphenylene ether compositions having improved flow | GENERAL ELECTRIC COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |