SCHEMBL13412893

SCHEMBL13412893

O=c1c2cc3[nH]c4c(Cl)c(Cl)ccc4c(=O)c3cc2[nH]c2c(Cl)c(Cl)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CSNK2A2 P19784 1/20 0.46
▸ CSNK2B P67870 1/20 0.46
▸ CSNK2A1 P68400 1/20 0.46
▸ CHUK O15111 1/20 0.44
▸ LIN28A Q9H9Z2 1/20 0.42
▸ STING1 Q86WV6 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ PARP1 P09874 1/20 0.37
▸ DYRK1A Q13627 1/20 0.37
▸ TP53 P04637 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ AR P10275 2/20 0.36
▸ CCNE2 O96020 1/20 0.36
▸ CDK4 P11802 1/20 0.36
▸ CCND1 P24385 1/20 0.36
▸ CCNE1 P24864 1/20 0.36
▸ CDK2 P24941 1/20 0.36
▸ CAMK2B Q13554 1/20 0.36
▸ CAMK2G Q13555 1/20 0.36
▸ CAMK2D Q13557 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21027984 0.85 MEN1 (0.44) CSNK2A2CSNK2BCSNK2A1CHUKMAPT
SCHEMBL21027555 0.85 KDM4E (0.44) CSNK2A2CSNK2BCSNK2A1CHUKLIN28A
SCHEMBL20995436 0.82 GAA (0.57) CSNK2A2CSNK2BCSNK2A1MAPTDYRK1A
SCHEMBL21027987 0.81 AURKA (0.47) CSNK2A2CSNK2BCSNK2A1CHUKLIN28A
SCHEMBL21027406 0.81 KIF11 (0.49) CSNK2A2CSNK2BCSNK2A1CHUKLIN28A
SCHEMBL22865990 0.80 PIM1 (0.39) CSNK2A2CSNK2BCSNK2A1CHUKLIN28A
SCHEMBL4172883 0.78 DYRK1A (0.60) PARP1DYRK1ASMN1; SMN2LMNAPOLB
SCHEMBL29391821 0.78 DYRK1A (0.60) PARP1DYRK1ASMN1; SMN2LMNAPOLB
SCHEMBL13412886 0.76 DYRK1A (0.45) CHUKLIN28AMAPTDYRK1ACCNE2
SCHEMBL13412892 0.74 GRIN2D (0.44) CHUKMAPTPARP1DYRK1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7683365-B2 Image pickup device FUJIFILM CORPORATION (JP) 2010-03-23 — — US disclosed
US-7683365-B2 Image pickup device FUJIFILM CORPORATION (JP) 2010-03-23 — — US disclosed
Send feedback