Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.36 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336875 | 0.98 | CA1 (0.50) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL12241914 | 0.98 | CA1 (0.50) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL7895027 | 0.84 | EPHX1 (0.36) | CA1CA2CA4CES2CES1 | |
| SCHEMBL4112859 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL7323358 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL4112857 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL4112861 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL4127933 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL19336874 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL25662275 | 0.77 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039982-A1 | CRTH2 MODULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |