Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179608 | 0.95 | MAPT (0.51) | MAPTMMP14KCNH2ALDH1A1GAA | |
| SCHEMBL12955087 | 0.95 | MAPT (0.51) | MAPTMMP14KCNH2ALDH1A1GAA | |
| SCHEMBL9950674 | 0.89 | MMP14 (0.48) | MAPTMMP14ALDH1A1GAAPOLB | |
| SCHEMBL1461305 | 0.87 | MMP14 (0.47) | MAPTMMP14ALDH1A1GAAPOLB | |
| SCHEMBL531129 | 0.87 | MMP14 (0.47) | MAPTMMP14ALDH1A1GAAPOLB | |
| SCHEMBL17583820 | 0.85 | MAPT (0.61) | MAPTMMP14KCNH2ALDH1A1GAA | |
| SCHEMBL17583819 | 0.85 | MAPT (0.61) | MAPTMMP14KCNH2ALDH1A1GAA | |
| SCHEMBL9358518 | 0.85 | MAPT (0.53) | MAPTMMP14KCNH2ALDH1A1GAA | |
| SCHEMBL13417484 | 0.85 | MAPT (0.53) | MAPTMMP14KCNH2ALDH1A1GAA | |
| SCHEMBL9358516 | 0.85 | MAPT (0.53) | MAPTMMP14KCNH2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674405-B2 | Zeolites with incorporated dipolar nonlinear optical molecules in uniform orientation and preparation thereof | Industry-University Cooperation Foundation Sogang University (KR) | 2010-03-09 | — | — | US | disclosed |