SCHEMBL13417845

SCHEMBL13417845

CO[Si](CCc1ccc(C(C)[Si](OC)(OC)OC)cc1)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
CALM1 P0DP23 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 1/20 0.32
CYP2D6 P10635 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ADRB2 P07550 2/20 0.31
LMNA P02545 2/20 0.31
HIF1A Q16665 2/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
OPRM1 P35372 2/20 0.31
AOC3 Q16853 1/20 0.31
GALR3 O60755 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13417847 0.82 TAAR1 (0.36) TAAR1AOC3SIGMAR1
SCHEMBL139733 0.81 TAAR1 (0.43) CALM1SMN1; SMN2TAAR1LMNAAOC3
SCHEMBL928393 0.81 MAPT (0.34) KMT2AMAPTCALM1SMN1; SMN2HTT
SCHEMBL929335 0.81 MAPT (0.34) KMT2AMAPTSMN1; SMN2HTTCYP2D6
SCHEMBL18905410 0.81 MAPT (0.37) KMT2AMAPTCALM1SMN1; SMN2CYP2D6
SCHEMBL31078984 0.81 MAPT (0.34) KMT2AMAPTSMN1; SMN2HTTCYP2D6
SCHEMBL927966 0.81 MAPT (0.34) KMT2AMAPTCALM1SMN1; SMN2HTT
SCHEMBL21507482 0.79 ESR1 (0.34) KMT2AMAPTSMN1; SMN2HTTCYP2D6
SCHEMBL4291669 0.79 TAAR1 (0.41) CALM1SMN1; SMN2TAAR1AOC3SIGMAR1
SCHEMBL235152 0.79 ESR1 (0.36) SMN1; SMN2ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7676130-B2 Optical fiber coating compositions CORNING INCORPORATED (US) 2010-03-09 US disclosed