SCHEMBL235152

SCHEMBL235152

CO[Si](OC)(OC)C(C)c1ccc(C(C)[Si](OC)(OC)OC)cc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
PDCD1 Q15116 1/20 0.36
ESR2 Q92731 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
NFKB1 P19838 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TYR P14679 1/20 0.30
TRPA1 O75762 1/20 0.30
PTGS1 P23219 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27147585 0.93 CYP17A1 (0.34) ESR1PDCD1ESR2CD274
SCHEMBL760246 0.91 ESR1 (0.52) ESR1PDCD1ESR2CD274NFKB1
SCHEMBL927965 0.89 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL928392 0.89 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL27866274 0.89 CYP1A2 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL929334 0.89 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL27849335 0.89 ACACB (0.33) ESR1PDCD1ESR2CD274
SCHEMBL22551505 0.89 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL22551470 0.89 ESR1 (0.30) ESR1PDCD1ESR2CD274
SCHEMBL140535 0.87 TRPA1 (0.39) ALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090506-A1 MEDICAL DEVICE COATINGS AND METHODS SURMODICS, INC. (US) 2026-04-30 WO claimed
EP-4569015-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS Promega Corporation (US) 2025-06-18 EP claimed
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION 2024-02-22 US claimed
WO-2024036277-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION (US) 2024-02-15 WO claimed
WO-2022261559-A9 ANTIFOULING MATERIALS, COMPOSITIONS AND METHODS OF USE ACatechol, Inc. (US) 2023-11-30 WO claimed
US-20190015815-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION 2019-01-17 US claimed
EP-3426388-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2019-01-16 EP claimed
EP-2971324-B1 MICROWAVE INITIATION FOR DEPOSITION OF POROUS ORGANOSILICATE MATERIALS ON FABRICS US GOV SEC NAVY (US) 2018-01-31 EP claimed
US-9689111-B2 Microwave initiation for deposition of porous organosilicate materials on fabrics THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2017-06-27 US claimed
EP-2850140-B1 RADIATION CURABLE COMPOSITION, AND METHOD FOR PREPARING A HYBRID SOL-GEL LAYER ON A SURFACE OF A SUBSTRATE USING SAID COMPOSITION UNIVERSITÉ DE HAUTE ALSACE (FR) 2016-07-06 EP claimed
EP-1311589-A1 COPOLYMER SEALANT COMPOSITIONS AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 2003-05-21 EP claimed
US-20030072951-A1 Substrate for immobilizing physiological material, and method of fabricating same SAMSUNG SDI CO., LTD. (KR) 2003-04-17 US claimed
US-20030062263-A1 Sensors with variable response behavior HRL LABORATORIES, LLC 2003-04-03 US claimed
EP-1291655-A2 Substrate for immobilizing physiological material and method of fabricating same Samsung SDI Co., Ltd. (KR) 2003-03-12 EP claimed
US-20030009000-A1 Copolymer sealant compositions and method for making MOMENTIVE PERFORMANCE MATERIALS INC. 2003-01-09 US claimed
US-6451954-B1 COPOLYMER FROM 1,4-BIS(DIMETHYLHYDROXYSILYL)BENZENE AND TRIS((TRIFLUOROPROPYL)METHYL)CYCLOSILOXANE WITH CROSSLINKING AGENT AND CONDENSATION CATALYST GENERAL ELECTRIC COMPANY 2002-09-17 US claimed
WO-2002010258-A1 COPOLYMER SEALANT COMPOSITIONS AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 2002-02-07 WO claimed
US-6331500-B1 SHAPE-SELECTIVE ADSORBENTS AND CATALYSTS MODULATED WITH CROSSLINKED SILOXY MONOMERS; MICROPOROSITY CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-12-18 US claimed
EP-1069081-A2 Silicate material and process for fabricating silicate material LUCENT TECHNOLOGIES INC. (US) 2001-01-17 EP claimed
WO-1999010277-A1 FUNCTIONALIZED MOLECULAR SIEVES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1999-03-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS COXFA4L2, LOXL1, LOX ESR1 1005/4885PDCD1 4606/4885ESR2 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.