SCHEMBL13417899

SCHEMBL13417899

Brc1ccc2c(c1)c1cc(Br)ccc1n2-c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
LIG1 P18858 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRA6 Q16445 1/20 0.36
DNM1 Q05193 1/20 0.36
DNMT1 P26358 1/20 0.35
DCLK1 O15075 1/20 0.34
PRKD3 O94806 1/20 0.34
MAP4K4 O95819 1/20 0.34
CHEK2 O96017 1/20 0.34
CSF1R P07333 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26543949 0.95 L3MBTL1 (0.49) L3MBTL1ATMKDM4EALDH1A1RXFP1
SCHEMBL346914 0.94 L3MBTL1 (0.42) L3MBTL1ATMKDM4EALDH1A1RXFP1
SCHEMBL25806697 0.90 L3MBTL1 (0.42) L3MBTL1ATMKDM4EALDH1A1RXFP1
SCHEMBL26543933 0.88 L3MBTL1 (0.38) L3MBTL1ATMKDM4EALDH1A1RXFP1
SCHEMBL12879622 0.86 KDM4E (0.45) L3MBTL1ATMKDM4EALDH1A1MAPT
SCHEMBL12879632 0.86 KDM4E (0.45) L3MBTL1ATMKDM4EALDH1A1MAPT
SCHEMBL19837799 0.85 KDM4E (0.55) L3MBTL1ATMKDM4ERXFP1GABRA1
SCHEMBL17463416 0.85 L3MBTL1 (0.51) L3MBTL1ATMKDM4EALDH1A1RXFP1
SCHEMBL19305268 0.84 PPARG (0.35) L3MBTL1ATMKDM4EDNMT1
SCHEMBL9881172 0.84 MAPT (0.36) L3MBTL1ATMKDM4EALDH1A1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110407874-B Novel aryl phosphine organic photoelectric material based on carbazole unit as core and preparation method and application thereof 南京邮电大学 2021-08-10 CN disclosed
US-7678472-B2 Compound and organic light-emitting diode and display utilizing the same AU OPTRONICS CORP. (TW) 2010-03-16 US disclosed
CN-100427467-C Compound, organic light emitting diode comprising compound and display YOUDA PHOTOELECTRIC CO LTD (CN) 2008-10-22 CN disclosed
CN-1657588-A Compound, organic light emitting diode comprising compound and display YOUDA PHOTOELECTRIC CO LTD (CN) 2005-08-24 CN disclosed