Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452689 | 0.74 | TSHR (0.42) | KDM1AKCNH2MAOBRCOR1CYP2A6 | |
| SCHEMBL13382520 | 0.73 | BRD4 (0.44) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL15923297 | 0.72 | LMNA (0.55) | LMNABRD4MAPTSMN1; SMN2 | |
| SCHEMBL14804298 | 0.67 | HTR2A (0.54) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL20267090 | 0.65 | MEN1 (0.39) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL14804315 | 0.65 | KDM1A (0.48) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL265495 | 0.65 | KDM1A (0.48) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL883113 | 0.65 | KDM1A (0.68) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL12295868 | 0.65 | KDM1A (0.68) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL5612 | 0.63 | BRD4 (0.53) | KDM1AKCNH2MAOBRCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043721-A1 | OXIDASE INHIBITORS AND THEIR USE | ORYZON GENOMICS, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |