Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3370599 | 0.99 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL13422591 | 0.85 | SLC6A2 (0.39) | SMN1; SMN2TP53MAPTKCNH2 | |
| Hydrochloric Acid SCHEMBL3375634 | 0.84 | SLC6A2 (0.38) | SMN1; SMN2TP53KCNH2 | |
| SCHEMBL3374016 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL3376459 | 0.81 | TP53 (0.48) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL13422582 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3374464 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL3373094 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL3374362 | 0.79 | GPR119 (0.52) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL13422781 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |