Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875700 | 0.85 | ERN1 (0.50) | FFAR4SYKHTTSMN1; SMN2ACHE | |
| SCHEMBL10137021 | 0.84 | ACHE (0.58) | SMN1; SMN2ALDH1A1HPGDACHECYP2D6 | |
| SCHEMBL11690934 | 0.84 | SYK (0.47) | FFAR4SYKKCNH2ALDH1A1CYP2D6 | |
| SCHEMBL11689848 | 0.84 | ESR2 (0.56) | SYKKCNH2CYP2D6PDGFRBPDGFRA | |
| SCHEMBL6609680 | 0.83 | KCNH2 (0.53) | SYKKCNH2CYP2D6CYP1A1CYP1B1 | |
| SCHEMBL696471 | 0.81 | KCNH2 (0.45) | SYKKCNH2CYP2D6GRIN2BCYP1A1 | |
| SCHEMBL11425087 | 0.80 | CYP11B1 (0.55) | SYKKCNH2CYP2D6GRIN2B | |
| SCHEMBL31227831 | 0.80 | DRD1 (0.49) | SYKKCNH2ALDH1A1HPGDESR1 | |
| SCHEMBL1047261 | 0.79 | CYP1A1 (0.65) | SYKSMN1; SMN2ALDH1A1ACHECYP2D6 | |
| SCHEMBL29788333 | 0.78 | CCNT1 (0.55) | FFAR4KCNH2HTTPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043721-A1 | OXIDASE INHIBITORS AND THEIR USE | ORYZON GENOMICS, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |