Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | DCK | P27707 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370717 | 0.84 | GPR119 (0.43) | GPR119SCDKIT | |
| SCHEMBL3372018 | 0.84 | GPR119 (0.48) | GPR119 | |
| SCHEMBL8513552 | 0.70 | GPR119 (0.51) | GPR119 | |
| SCHEMBL3342636 | 0.70 | GPR119 (0.60) | GPR119 | |
| SCHEMBL12474776 | 0.70 | GPR119 (0.38) | GPR119 | |
| SCHEMBL2570672 | 0.69 | GPR119 (0.59) | GPR119 | |
| SCHEMBL2551042 | 0.69 | GPR119 (0.59) | GPR119 | |
| SCHEMBL12283007 | 0.69 | GPR119 (0.59) | GPR119 | |
| SCHEMBL1005428 | 0.69 | SCD (0.47) | GPR119SCD | |
| SCHEMBL3178150 | 0.69 | GPR119 (0.54) | GPR119SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |