Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565348 | 0.81 | CTSK (0.38) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL30030533 | 0.79 | HDAC6 (0.34) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL27776766 | 0.77 | HDAC6 (0.33) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL16751219 | 0.77 | HDAC6 (0.33) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL16751229 | 0.77 | HDAC6 (0.33) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL31757873 | 0.75 | MEN1 (0.33) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL1447140 | 0.74 | HDAC6 (0.36) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL13490197 | 0.74 | HDAC6 (0.36) | CTSKHDAC6HDAC1HDAC2CACNA1G | |
| SCHEMBL3157411 | 0.73 | HDAC1 (0.31) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL31757748 | 0.73 | CA14 (0.33) | CTSKHDAC6HDAC1HDAC2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042851-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2010-04-15 | — | — | WO | disclosed |