Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285692 | 0.90 | MEN1 (0.71) | MEN1KMT2AFLT3KIF11PTGS2 | |
| SCHEMBL2290102 | 0.82 | MEN1 (0.58) | MEN1KMT2AFLT3KIF11PTGS2 | |
| SCHEMBL2818000 | 0.76 | MEN1 (0.56) | MEN1KMT2AFLT3KIF11CCNB2 | |
| SCHEMBL2284207 | 0.76 | PPARG (0.63) | MEN1KMT2AFLT3PTGS2KDM4E | |
| SCHEMBL29031872 | 0.76 | PARP1 (0.59) | MEN1KMT2AFLT3KIF11CCNB2 | |
| SCHEMBL30472344 | 0.76 | PARP1 (0.59) | MEN1KMT2AFLT3KIF11CCNB2 | |
| SCHEMBL10746161 | 0.75 | MEN1 (0.57) | MEN1KMT2AFLT3KIF11CCNB2 | |
| SCHEMBL5441431 | 0.74 | MEN1 (0.54) | MEN1KMT2AFLT3KIF11CCNB2 | |
| SCHEMBL7040925 | 0.74 | ESR1 (0.68) | MEN1KMT2AFLT3KIF11PTGS2 | |
| SCHEMBL11558711 | 0.74 | MEN1 (0.69) | MEN1KMT2AFLT3KIF11CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046013-A1 | AZAINDOLE DERIVATIVE | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |