Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30472344 | 1.00 | PARP1 (0.59) | PARP1MEN1KMT2AKIF11TNKS | |
| SCHEMBL2285692 | 0.84 | MEN1 (0.71) | PARP1MEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL29639192 | 0.79 | SERPINE1 (0.56) | SERPINE1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL29639258 | 0.76 | PTGS2 (0.54) | MEN1KMT2ASERPINE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29639197 | 0.76 | SERPINE1 (0.53) | SERPINE1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13423978 | 0.76 | MEN1 (0.59) | PARP1MEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL29031853 | 0.75 | PDE3B (0.48) | MEN1KMT2ATNKSSERPINE1ALDH1A1 | |
| SCHEMBL29031864 | 0.75 | SERPINE1 (0.51) | PARP1SERPINE1ALDH1A1KDM4EHPGD | |
| SCHEMBL2290102 | 0.75 | MEN1 (0.58) | MEN1KMT2AKIF11MAPK1SMN1; SMN2 | |
| SCHEMBL25293367 | 0.74 | PARP1 (1.00) | PARP1MEN1KMT2AKIF11TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396206-A | Isoindolinone compound and preparation method and application thereof | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |