Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381266 | 0.79 | LMNA (0.67) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL9898531 | 0.79 | LMNA (0.66) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL2819531 | 0.78 | KMT2A (0.54) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11264123 | 0.78 | LMNA (0.54) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL29994009 | 0.78 | KMT2A (0.69) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL50006 | 0.78 | LMNA (0.64) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL8154526 | 0.78 | LMNA (0.74) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| Benzene SCHEMBL28006345 | 0.78 | KMT2A (0.69) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL301123 | 0.78 | KMT2A (0.69) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11032435 | 0.77 | LMNA (0.52) | LMNAMEN1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |