Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425609 | 0.94 | KCNH2 (0.49) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL3399224 | 0.93 | KCNH2 (0.47) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL13425784 | 0.93 | KCNH2 (0.52) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL13425597 | 0.91 | KCNH2 (0.50) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL13426244 | 0.91 | KCNH2 (0.50) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL13425632 | 0.90 | KCNH2 (0.49) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL13426216 | 0.89 | KCNH2 (0.48) | KCNH2MAPK1CLK4DYRK1AHRH2 | |
| SCHEMBL3399662 | 0.88 | KCNH2 (0.51) | KCNH2MAPK1CLK4CHEK1ALDH1A1 | |
| SCHEMBL13426311 | 0.88 | KCNH2 (0.47) | KCNH2CHEK1BDKRB1 | |
| SCHEMBL13425790 | 0.86 | KCNH2 (0.56) | KCNH2MAPK1CLK4DYRK1AHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |