Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425784 | 0.88 | KCNH2 (0.52) | KCNH2LRRK2CHEK1 | |
| SCHEMBL13425751 | 0.88 | KCNH2 (0.51) | KCNH2BDKRB1CHEK1 | |
| SCHEMBL13425597 | 0.87 | KCNH2 (0.50) | KCNH2LRRK2CHEK1EGLN1FASN | |
| SCHEMBL13425632 | 0.86 | KCNH2 (0.49) | KCNH2EGLN1FASN | |
| SCHEMBL13425609 | 0.85 | KCNH2 (0.49) | KCNH2CHEK1SMN1; SMN2 | |
| SCHEMBL13426216 | 0.85 | KCNH2 (0.48) | KCNH2EGLN1 | |
| SCHEMBL3399224 | 0.84 | KCNH2 (0.47) | KCNH2CHEK1EGLN1 | |
| SCHEMBL13425790 | 0.84 | KCNH2 (0.56) | KCNH2CAMKK2TNIKCHEK1 | |
| SCHEMBL3399662 | 0.84 | KCNH2 (0.51) | KCNH2CHEK1NPC1HTTRAB9A | |
| SCHEMBL13426244 | 0.82 | KCNH2 (0.50) | KCNH2LRRK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |