SCHEMBL13428296

SCHEMBL13428296

CC[n+]1ccc(C=Cc2ccc(N(C)C)cc2)c2ccccc21

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.97
RAB9A P51151 6/20 0.97
KMT2A Q03164 6/20 0.97
HTT P42858 5/20 0.97
NPC1 O15118 4/20 0.97
POLB P06746 4/20 0.97
NPSR1 Q6W5P4 4/20 0.97
L3MBTL1 Q9Y468 3/20 0.97
PKM P14618 3/20 0.97
ALDH1A1 P00352 3/20 0.97
MAPT P10636 3/20 0.97
LMNA P02545 3/20 0.97
RAD52 P43351 2/20 0.97
NSD2 O96028 2/20 0.97
PPARG P37231 2/20 0.97
NCOA2 Q15596 2/20 0.97
NCOA1 Q15788 2/20 0.97
THRB P10828 2/20 0.97
MAPK1 P28482 2/20 0.97
RECQL P46063 2/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036010 1.00 MEN1 (0.97) MEN1RAB9AKMT2AHTTNPC1
Iodide SCHEMBL11803644 0.99 MEN1 (1.00) MEN1RAB9AKMT2AHTTNPC1
SCHEMBL5701148 0.92 RAB9A (0.84) MEN1RAB9AKMT2AHTTNPC1
SCHEMBL140322 0.92 RAB9A (0.84) MEN1RAB9AKMT2AHTTNPC1
SCHEMBL14562208 0.88 MEN1 (0.77) MEN1RAB9AKMT2AHTTNPC1
SCHEMBL14984123 0.88 MEN1 (0.77) MEN1RAB9AKMT2AHTTNPC1
Perchlorate SCHEMBL1405333 0.88 RAB9A (0.77) MEN1RAB9AKMT2AHTTNPC1
Perchlorate SCHEMBL7130210 0.88 RAB9A (0.77) MEN1RAB9AKMT2AHTTNPC1
SCHEMBL14984119 0.87 MEN1 (0.76) MEN1RAB9AKMT2AHTTNPC1
SCHEMBL18104413 0.87 MEN1 (0.76) MEN1RAB9AKMT2AHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9222934-B2 Reagent and reagent kit for analysis of immature leukocyte SYSMEX CORPORATION (JP) 2015-12-29 US disclosed
US-8859200-B2 Reagent and reagent kit for analysis of immature leukocyte SYSMEX CORPORATION (JP) 2014-10-14 US disclosed
US-8766238-B2 Polymeric anions/cations MERCK PATENT GMBH (DE) 2014-07-01 US disclosed
EP-2166354-A1 REAGENT AND REAGENT KIT FOR ANALYSIS OF PRIMITIVE LEUKOCYTE Sysmex Corporation (JP) 2010-03-24 EP disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 US disclosed