Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | SDHA | P31040 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CALML3 | P27482 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428639 | 0.91 | MAOB (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428249 | 0.90 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428373 | 0.89 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428443 | 0.86 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL12527868 | 0.86 | MAOA (0.67) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428439 | 0.85 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428219 | 0.84 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428548 | 0.84 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428146 | 0.84 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13428673 | 0.84 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |