Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.48 |
| ▸ | MAOA | P21397 | 9/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SDHA | P31040 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969138 | 0.91 | CALML3 (0.48) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL11969134 | 0.85 | MAOA (0.58) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL13428680 | 0.78 | MAOA (0.59) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL11969173 | 0.78 | MAOA (0.59) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL11968861 | 0.78 | MAOA (0.62) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL13428754 | 0.77 | MAOA (0.55) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL11969270 | 0.77 | MAOA (0.55) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL11969868 | 0.76 | MAOA (0.56) | MAOAMAOBCYP3A4 | |
| SCHEMBL11969254 | 0.76 | MAOA (0.49) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL11969478 | 0.75 | CALML3 (0.47) | CALML3MAOACYP2C19CYP2C9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |