Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SDHA | P31040 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428653 | 0.87 | CALML3 (0.56) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL23992025 | 0.80 | F10 (0.44) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL23992014 | 0.80 | F10 (0.44) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL13428297 | 0.78 | F10 (0.43) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL1222787 | 0.78 | CALML3 (0.67) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL10033715 | 0.78 | CALML3 (0.67) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL1222791 | 0.78 | CALML3 (0.67) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL12527840 | 0.78 | CALML3 (0.57) | CALML3CYP2C19CYP3A4MAOBMAOA | |
| SCHEMBL13428553 | 0.77 | MAOA (0.61) | CALML3MAOBMAOAF10LMNA | |
| SCHEMBL3323285 | 0.77 | CALML3 (0.80) | CALML3CYP2C19CYP3A4MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |