Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.34 |
| ▸ | CALML3 | P27482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SDHA | P31040 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969138 | 0.81 | CALML3 (0.48) | MAOAMAOBCALML3 | |
| SCHEMBL11968861 | 0.80 | MAOA (0.62) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL11969270 | 0.80 | MAOA (0.55) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL13428754 | 0.80 | MAOA (0.55) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL11969254 | 0.78 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL11969086 | 0.78 | CYP2E1 (0.57) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL11969868 | 0.75 | MAOA (0.56) | MAOAMAOB | |
| SCHEMBL13428879 | 0.74 | MAOA (0.61) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL11969552 | 0.74 | MAOA (0.61) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL13428679 | 0.74 | MAOA (0.37) | MAOAMAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |