Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 15/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969777 | 1.00 | MAOA (0.52) | MAOACYP2E1F10CYP1A2CYP3A4 | |
| SCHEMBL11969741 | 0.88 | MAOA (0.59) | MAOACYP2E1F10MAOB | |
| SCHEMBL6766071 | 0.83 | MAOA (0.57) | MAOACYP2E1F10CYP1A2CYP3A4 | |
| SCHEMBL11969046 | 0.82 | MAOA (0.50) | MAOACYP2E1F10MAOB | |
| SCHEMBL15830205 | 0.81 | MAOA (0.58) | MAOACYP2E1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12964777 | 0.81 | MAOA (0.58) | MAOACYP2E1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11968859 | 0.79 | MAOA (0.56) | MAOAF10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11971864 | 0.79 | GRM2 (0.44) | F10 | |
| SCHEMBL11969175 | 0.79 | CALML3 (0.50) | MAOAF10CYP2C9CYP2C19MAOB | |
| SCHEMBL11969009 | 0.77 | F10 (0.45) | MAOAF10CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |