Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of L-Alaninol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Alaninol SCHEMBL11142156 | 0.91 | TP53 (0.44) | TP53TSHRCA5ACA5BALDH1A1 | |
| L-Alaninol SCHEMBL11150399 | 0.88 | TP53 (0.48) | TP53TSHRALDH1A1TDP1GABRP | |
| L-Alaninol SCHEMBL2804901 | 0.83 | TSHR (0.54) | TP53TSHRALDH1A1TDP1GABRP | |
| L-Alaninol SCHEMBL82137 | 0.83 | — | — | |
| L-Alaninol SCHEMBL30499 | 0.83 | — | — | |
| L-Alaninol SCHEMBL30417235 | 0.83 | — | — | |
| L-Alaninol SCHEMBL7787362 | 0.83 | TSHR (0.54) | TP53TSHRALDH1A1TDP1GABRP | |
| L-Alaninol SCHEMBL1331749 | 0.83 | — | — | |
| L-Alaninol SCHEMBL72189 | 0.83 | — | — | |
| Sulfuric Acid SCHEMBL5855410 | 0.82 | TP53 (0.60) | TP53TSHRCA5ACA5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063007-B2 | Removing agent composition and removing/cleaning method using same | KAO CORPORATION (JP) | 2011-11-22 | — | — | US | claimed |
| CN-102584606-B | Method for preparing aminopropanol by bipolar membrane electrodialysis | UNIV ZHEJIANG TECHNOLOGY | 2014-01-29 | — | — | CN | disclosed |
| CN-102584606-A | Method for preparing aminopropanol by bipolar membrane electrodialysis | UNIV ZHEJIANG TECHNOLOGY | 2012-07-18 | — | — | CN | disclosed |
| US-8063007-B2 | Removing agent composition and removing/cleaning method using same | KAO CORPORATION (JP) | 2011-11-22 | — | — | US | disclosed |
| US-20090247447-A1 | REMOVING AGENT COMPOSITION AND REMOVING/CLEANING METHOD USING SAME | TAMURA ATSUSHI | 2009-10-01 | — | — | US | disclosed |
| US-20060293199-A1 | Removing agent composition and removing/cleaning method using same | KAO CORPORATION (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1638138-A1 | REMOVING AGENT COMPOSITION AND REMOVING/CLEANING METHOD USING SAME | Kao Corporation (JP) | 2006-03-22 | — | — | EP | disclosed |