4,4'-Oxybis(Nitrobenzene)

4,4'-Oxybis(Nitrobenzene)

SCHEMBL134332

O=[N+]([O-])c1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 2/20 0.79
KMT2A Q03164 5/20 0.66
MEN1 O00255 4/20 0.66
MAPT P10636 3/20 0.66
MAPK1 P28482 2/20 0.66
NPC1 O15118 1/20 0.66
RAB9A P51151 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
MYOC Q99972 1/20 0.66
ALDH1A1 P00352 4/20 0.63
SRD5A2 P31213 1/20 0.63
HTT P42858 1/20 0.58
KDM4E B2RXH2 1/20 0.58
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA9 Q16790 1/20 0.57
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
LMNA P02545 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2011179 1.00 HSPB1 (0.79) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL9183872 1.00 HSPB1 (0.79) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL11689190 1.00 HSPB1 (0.79) HSPB1KMT2AMEN1MAPTMAPK1
4,4'-Oxybis(Nitrobenzene) SCHEMBL8934595 0.97 HSPB1 (0.76) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL28051442 0.93 HSPB1 (0.70) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL311582 0.93 KMT2A (0.73) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL3208134 0.93 HSPB1 (0.70) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL11191189 0.91 HSPB1 (0.68) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL457863 0.91 HSPB1 (0.68) HSPB1KMT2AMEN1MAPTMAPK1
SCHEMBL23385506 0.89 HSPB1 (0.66) HSPB1KMT2AMEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2221 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4723888-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS Speedagro Inc. (US) 2026-04-15 EP claimed
US-20250176551-A1 METHOD FOR CONTROLLING THE GROWTH OF UNDESIRABLE VEGETATION UPL LTD (IN) 2025-06-05 US claimed
CN-119822975-A Method for synthesizing 4,4' -diaminodiphenyl ether by catalytic transfer hydrogenation 山东师范大学 2025-04-15 CN claimed
CN-119822962-A Solvent-free method for synthesizing 4,4' -dinitrodiphenyl ether 山东省分析测试中心 2025-04-15 CN claimed
US-20250113826-A1 AN AGROCHEMICAL COMBINATION UPL LTD (IN) 2025-04-10 US claimed
CN-119390589-A Method for preparing 4,4' -diaminodiphenyl ether 河北工业大学 2025-02-07 CN claimed
WO-2024254580-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS SPEEDAGRO INC. (US) 2024-12-12 WO claimed
CN-118771992-A Method for synthesizing 4,4' -diaminodiphenyl ether by continuous catalytic hydrogenation 衢州市浙工大生态工业创新研究院 2024-10-15 CN claimed
CN-118652184-A Synthesis method of diaminodiphenyl ether 阜阳市诗雅涤新材料科技有限公司 2024-09-17 CN claimed
CN-221470997-U P-nitrodiethyl ether washing system 江苏中丹化工技术有限公司 2024-08-06 CN claimed
EP-0507616-B1 Process for the preparation of trisubstituted ureas by reductive carbonylation ARCO CHEM TECH (US) 1996-02-07 EP claimed
EP-0379099-B1 Tetrahydroindazoles with a phenyl ether structure BASF AG (DE) 1994-09-14 EP claimed
US-5241118-A Reacting nitroarene with carbon monoxide ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-08-31 US claimed
EP-0313963-B1 N-PHENYLTETRAHYDROPHTHALIMIDE DERIVATIVES BASF Aktiengesellschaft (DE) 1992-12-23 EP claimed
EP-0507616-A1 Process for the preparation of trisubstituted ureas by reductive carbonylation ARCO Chemical Technology, L.P. (US) 1992-10-07 EP claimed
EP-0367242-A2 Aryloxy benzotriazole herbicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1990-05-09 EP claimed
EP-0055693-B1 USE OF PHENYL PYRIMIDINES AS PROTECTING AGENTS FOR CULTURE PLANTS AGAINST PHYTOTOXIC DAMAGE CAUSED BY HERBICIDES CIBA-GEIGY AG (CH) 1988-01-20 EP claimed
US-4700011-A Methods for the production and purification of di (nitrophenyl) ethers AMOCO CORPORATION (US) 1987-10-13 US claimed
US-4558164-A Production of dinitrodiphenyl ether E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-10 US claimed
US-4178455-A FROM AROMATIC NITRO COMPOUND, ALCOHOL AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-12-11 US claimed