Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416072 | 0.95 | HPGD (0.51) | PPARAPPARDGAAMAPTNPC1 | |
| SCHEMBL3419218 | 0.94 | PPARA (0.51) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL3417120 | 0.91 | PPARA (0.49) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL3418419 | 0.91 | PPARA (0.54) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL3418656 | 0.88 | KDM4E (0.58) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL3416639 | 0.88 | XDH (0.47) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL3418681 | 0.87 | PPARA (0.46) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL13460828 | 0.87 | PPARA (0.45) | PPARAPPARDGAAKDM4ERAB9A | |
| SCHEMBL6865441 | 0.86 | PPARA (0.45) | PPARAPPARDKDM4ERAB9AMAPT | |
| SCHEMBL3416366 | 0.85 | TSHR (0.45) | PPARAPPARDGAAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |