Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418800 | 0.91 | KMT2A (0.48) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL13433238 | 0.90 | PPARG (0.58) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL13460772 | 0.87 | HPGD (0.54) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL13461037 | 0.85 | HPGD (0.52) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL3417177 | 0.81 | PPARG (0.52) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL6865441 | 0.80 | PPARA (0.45) | HPGDALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL6503265 | 0.78 | HPGD (0.56) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL5037078 | 0.76 | HPGD (0.51) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL5552687 | 0.76 | HPGD (0.53) | HPGDALDH1A1HSD17B10KDM4ENPSR1 | |
| SCHEMBL6887732 | 0.76 | HPGD (0.51) | HPGDALDH1A1HSD17B10KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |