Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410598 | 0.91 | PSEN1 (0.45) | EPHX2PPARGPPARDPPARATRPV1 | |
| SCHEMBL3410602 | 0.91 | PSEN1 (0.45) | EPHX2PPARGPPARDPPARATRPV1 | |
| SCHEMBL13433343 | 0.84 | FDPS (0.47) | PPARGPPARDPPARATRPV1ALDH1A1 | |
| SCHEMBL3413605 | 0.83 | PPARG (0.45) | PPARGPPARDPPARATRPV1ALDH1A1 | |
| SCHEMBL13433354 | 0.81 | SYK (0.45) | EPHX2PPARGPPARDPPARATRPV1 | |
| SCHEMBL3413325 | 0.79 | PDCD1 (0.45) | PPARGPPARDPPARAALDH1A1PKM | |
| SCHEMBL3413329 | 0.79 | PDCD1 (0.45) | PPARGPPARDPPARAALDH1A1PKM | |
| SCHEMBL3418629 | 0.76 | PPARA (0.45) | PPARGPPARDPPARATRPV1HTT | |
| SCHEMBL3416346 | 0.76 | PPARG (0.53) | PPARGPPARDPPARATRPV1ALDH1A1 | |
| SCHEMBL3415307 | 0.76 | PPARD (0.63) | EPHX2PPARGPPARDPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |