Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.62 |
| ▸ | PPARA | Q07869 | 15/20 | 0.62 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415748 | 0.91 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL13433442 | 0.90 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL3415075 | 0.87 | PPARD (0.79) | PPARDPPARAPPARG | |
| SCHEMBL13433429 | 0.87 | PPARD (0.47) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL13433430 | 0.87 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL13460810 | 0.87 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL3418675 | 0.87 | PPARA (0.83) | PPARDPPARAPPARG | |
| SCHEMBL3417343 | 0.86 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL3413986 | 0.85 | PTGDR2 (0.61) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL3418634 | 0.85 | PPARD (0.69) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |