Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.47 |
| ▸ | PPARA | Q07869 | 9/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433429 | 0.89 | PPARD (0.47) | PPARDPPARAPPARGNR1H4ROCK2 | |
| SCHEMBL13433432 | 0.87 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL13433426 | 0.81 | PPARD (0.47) | PPARDPPARAPPARGNR1H4TMEM97 | |
| SCHEMBL13433441 | 0.79 | PPARD (0.56) | PPARDPPARAPPARGPTPN11 | |
| SCHEMBL3415748 | 0.79 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL13433435 | 0.78 | PPARA (0.48) | PPARDPPARAPPARGNR1H4ROCK2 | |
| SCHEMBL13433442 | 0.77 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL13433434 | 0.76 | PPARA (0.47) | PPARDPPARAPPARGPTPN11ROCK2 | |
| SCHEMBL3413822 | 0.76 | PPARD (0.61) | PPARDPPARAPPARGROCK2ROCK1 | |
| SCHEMBL3415779 | 0.75 | PPARD (0.51) | PPARDPPARAAKR1B1PPARGROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |