Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 7/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417421 | 0.97 | PPARA (0.54) | HPGDNPC1PPARAPPARDPPARG | |
| SCHEMBL3415741 | 0.96 | PPARA (0.51) | HPGDNPC1PPARAPPARDPPARG | |
| SCHEMBL3419117 | 0.94 | PPARA (0.54) | HPGDNPC1PPARAPPARDPPARG | |
| SCHEMBL3416671 | 0.88 | RAB9A (0.48) | NPC1PPARAPPARDPPARGSMN1; SMN2 | |
| SCHEMBL3413127 | 0.84 | PPARA (0.56) | HPGDNPC1PPARAPPARDPPARG | |
| SCHEMBL3413821 | 0.83 | PPARA (0.53) | HPGDNPC1PPARAPPARDSMN1; SMN2 | |
| SCHEMBL3416911 | 0.82 | PPARA (0.51) | HPGDNPC1PPARAPPARDPPARG | |
| SCHEMBL3415767 | 0.81 | PPARA (0.60) | HPGDNPC1PPARAPPARDPPARG | |
| SCHEMBL3418668 | 0.81 | PPARA (0.55) | NPC1PPARAPPARDPPARGSMN1; SMN2 | |
| SCHEMBL3413992 | 0.80 | PPARA (0.54) | NPC1PPARAPPARDPPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |