Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.56 |
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA4 | P22748 | 7/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435708 | 0.88 | CA2 (0.60) | CA2CA1CA4CA12CA3 | |
| SCHEMBL13435695 | 0.87 | CA2 (0.72) | CA2CA1CA4CA12CA3 | |
| SCHEMBL13435710 | 0.86 | CA2 (0.78) | CA2CA1CA4CA12CA3 | |
| SCHEMBL18656745 | 0.81 | CA2 (0.57) | CA2CA1CA4CA12CA3 | |
| SCHEMBL18656663 | 0.81 | CA2 (0.57) | CA2CA1CA4CA12CA3 | |
| SCHEMBL13435705 | 0.79 | CA2 (0.58) | CA2CA1CA4CA12CA3 | |
| SCHEMBL18656659 | 0.79 | CA2 (0.59) | CA2CA1CA4CA12CA3 | |
| SCHEMBL13435706 | 0.78 | CA2 (0.78) | CA2CA1CA4CA12CA3 | |
| SCHEMBL23643556 | 0.78 | CA2 (0.53) | CA2CA1CA4CA12CA3 | |
| SCHEMBL18656748 | 0.76 | CA2 (0.58) | CA2CA1CA4CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063035-A1 | CARBONIC ANHYDRASE INHIBITORS DERIVATIVES | NICOX S.A. (FR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063035-A1 | CARBONIC ANHYDRASE INHIBITORS DERIVATIVES | CA4, CA2, CA9 | CA2 2/4885CA1 71/4885CA4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.