Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433107 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL27792099 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL28459939 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL3084308 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL24968118 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL16665613 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL15479668 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL28841025 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL15221142 | 0.71 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.71 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056432-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIBACTERIAL ACTIVITY | POLYPHOR LTD. (CH) | 2010-03-04 | — | — | US | disclosed |
| US-7582604-B2 | Template-fixed peptidomimetics with antibacterial activity | POLYPHOR LTD. (CH) | 2009-09-01 | — | — | US | disclosed |
| US-7417024-B2 | Template-fixed peptidomimetics as inhibitors of serine proteases | POLYPHOR LTD. (CH) | 2008-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056432-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIBACTERIAL ACTIVITY | POLL, QPCTL, PEPD | ALDH1A1 1705/4885MAPT 2899/4885HPGD 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.