Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535707 | 1.00 | KYNU (0.57) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL1110994 | 0.99 | KYNU (0.56) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL269404 | 0.93 | KYNU (0.62) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL187849 | 0.93 | KYNU (0.62) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL29678939 | 0.93 | KYNU (0.62) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL19410220 | 0.92 | KYNU (0.57) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL13798138 | 0.90 | KYNU (0.56) | KYNUELANEATMKLK1CTRB1 | |
| Lithium Ion SCHEMBL1110992 | 0.89 | KYNU (0.55) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL15549899 | 0.86 | ELANE (0.54) | KYNUELANEATMKLK1CTRB1 | |
| SCHEMBL13798136 | 0.86 | KYNU (0.52) | KYNUELANEATMKLK1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177523-A1 | Novel macrocyclic inhibitors of hepatitis c virus replication | Intermune, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |