Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13798443 | 1.00 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL8172844 | 0.96 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL13798426 | 0.95 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL13435828 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13435829 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13798444 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13435749 | 0.94 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13435917 | 0.94 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL8171334 | 0.94 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13798450 | 0.93 | DDB1 (0.35) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177523-A1 | Novel macrocyclic inhibitors of hepatitis c virus replication | Intermune, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |